The primary objective of the BS degree program in Molecular Cell Biology is to prepare students for careers in fields that require advanced knowledge of molecular biology, in particular those that relate to human health and welfare. Examples of such fields include, but are not limited to, medicine, pharmacology, pathology, genetic testing and counseling, biotechnology, nanotechnology, teaching, and basic research. The proposed program will focus on the molecular biology of eukaryotic organisms, which sets it apart from the current program in Microbiology, which focuses on prokaryotic organisms. It will emphasize our understanding of the molecular biology of human health, disease and treatment, differentiating it from the existing Biology program. The second objective and natural consequence of a program in Molecular Cell Biology is human resource support for the medical school, UH graduate programs, and biotechnology businesses that provide services and economic opportunities to communities throughout the state of Hawaiʻi.
The seven learning objectives for the MCB program can be grouped into three broad categories: cognitive, skills-based and values-based.
SLO 1 – Graduates of the MCB program will be able to explain and discuss how processes are integrated at the molecular level to create a functional eukryotic cell.
SLO 2 – Graduates of the MCB program will be able to describe the structures and various cellular functions associated with the macromolecules found in cells.
SLO 3 – Graduates of the MCB program will be able to explain the techniques and logic of methods employed in molecular biology research.
SLO 4 - Graduates of the MCB program will be able to explain the molecular basis of human diseases and research on prospective treatments.
SLO 5 - Graduates of the MCB program will have experience in and be able to perform techniques employed in molecular biology research:
SLO 6 – Graduates of the MCB program will be able to critically evaluate scientific studies:
SLO 7 Graduates of the MCB program will be able to evaluate the ethical implications of research methods and outcomes.
To earn a BS degree in Molecular Cell Biology, all candidates will be required to complete the college program requirements for the BS degree, which includes fulfilling any Arts and Sciences requirement and UHM General Education requirements. Consult with a life sciences advisor.
The course requirements for the BS degree in MCB can be divided into three categories: basic science, MCB core, and MCB elective courses, details of which are listed below. Basic science courses are intended to prepare students for upper-level coursework. MCB core courses form the foundation of the degree. And, MCB elective courses allow students to tailor their degree to suit their needs and interests. The number of program credits is intended to allow students to graduate with a competitive BS degree in MCB in four years.
The MCB core courses were chosen for the following reasons. Genetics and Biochemistry traditionally serve as basis of any program in molecular cell biology. They describe the basic concepts of molecular interactions required for understanding how the constituents of a cell carry out basic cellular functions. Cellular Biology and Molecular Biology form the heart of the program, integrating the basic concepts of biochemistry and genetics with organelle and sub-cellular functions to describe a living cell. In addition to focusing the program on human health and disease processes, Immunology and the Biology of Cancer challenge students to apply their basic knowledge of molecular cell biology in more specialized fields, two of the most heavily researched fields in all of biology and healthcare. Finally, Research Ethics equips students with the tools necessary to identify and evaluate the ethics of research in molecular cell biology and its potential outcomes for research subjects, researchers, and society.
Elective courses allow students to apply their basic knowledge of molecular cell biology in more specialized fields of their choice.
|4||BIOL172+172L, Introduction to Biology II|
|4||BIOL275+275L, Cell and Molecular Biology|
|8||CHEM161+161L & CHEM162+162L, General Chemistry I & II|
|8||CHEM272+272L & CHEM273, Organic Chemistry I & II|
|7 or 8||Either MATH215 & MATH216, Applied Calculus I & II or MATH241 & MATH242, Calculus I & II|
|8 or 9||Either PHYS151-151L & PHYS152-152L, College Physics I & II or PHYS170-170L & PHYS272-272L, General Physics I & II|
|4||BIOL375+375L, Concepts of Genetics|
|4||MBBE/BIOL402 or BIOC441, Biochemistry|
|3||BIOL407, Molecular Biology (Molecular Cell Biology I)|
|3||MBBE/BIOL408 Molecular Cell Biology II (formerly BIOL406)|
|2||BIOL408L Cell Biology Lab (currently not available)|
|3||MCB472, Biology of Cancer (Capstone course)|
|1||MCB314, Research Ethics|
Minimum 11 credits, to include 2 laboratory classes
|1-3||BIOL/BOT/ZOOL/MICR499, Directed Research|
|3||ICS475, Intro to Bioinformatics Sequences and Genomes Analysis|
|4||MATH304, Mathematical Modeling I Deterministic Models|
|4||MATH305, Mathematical Modeling II Probabilistic Models|
|5||MICR351/351L, Biology of Microorganisms|
|3 or 5||MICR431+ optional 431L, Microbial Physiology|
|3||MICR470, Microbial Pathogenesis|
|3 or 5||MICR475 + optional 475L, Bacterial Genetics|
|3 or 5||MICR490 + optional 490L, Animal Virology|
|3||MBBE405, Microbial Biotechnology|
|4 or 5||PHYL301 + optional 301L, Human Anatomy and Physiology|
|3 or 5||ZOOL420 + optional 420L, Developmental Biology|
|3||ZOOL442, Introduction to Neuroscience|
|Select graduate-level courses by permission|